[Diabetic vasculopathy, its relation to hypoglycemic agent use, the time of evolution and patient age]
C M Hernández Cañete1, J Tejidor Fernández, R Segura Macias
1Hospital Provincial Docente Dr. Antonio Luaces Iraola, Ciego de Avila, Cuba.
Insights
Diabetes Mellitus patients on oral hypoglycemic agents showed significantly higher lower limb obstruction. Long-term high blood glucose and older age are key factors in diabetic vasculopathy incidence.
Area of Science:
- Vascular Medicine
- Endocrinology
- Diabetology
Context:
- Study conducted on 404 patients with Diabetes Mellitus admitted to Angiology Services in Camaguey and Ciego de Avila.
- Analysis focused on injury type, lower limb obstruction level, diabetes type, and treatment received.
Purpose:
- To investigate the relationship between diabetes type, treatment, disease duration, age, and the level of lower limb obstruction in diabetic patients.
- To identify key factors contributing to the high incidence of vasculopathy in patients with Diabetes Mellitus.
Summary:
- No significant relation was found between the type of Diabetes Mellitus and the level of lower limb obstruction.
- Patients treated with oral hypoglycemic agents exhibited a higher degree of obstruction compared to other treatment groups.
- Disease duration and patient age showed a direct correlation with the presence of vasculopathy.
Impact:
- Identifies oral hypoglycemic agents as potentially associated with increased obstruction risk.
- Highlights long-term hyperglycemia and advanced age as critical risk factors for diabetic vasculopathy.
- Provides insights for targeted interventions and management strategies to prevent lower limb complications in diabetic patients.
Abstract:
The present study includes 404 patients with Diabetes Mellitus, admitted into the Angiology Service from the Hospital Provincial Docente Manuel Ascunse Domenech, Camaguey and from Dr. Antonio Luaces Iraola, Ciego de Avila. Type of injury, level of obstruction at the lower limbs, type of diabetes and treatment received for each patient were analyzed. Preliminary conclusions are: no relation was found between type of diabetes and level of obstruction; and the second conclusion was that patients receiving oral hypoglicemiants presented more obstruction, with a significant difference by the square test. Time of disease and age of patient had a direct correlation with the presence of vasculopathy. Finally, it should be noted that high level of glicemy during a long period of time and elderly patients are the main factors implicated in the high incidence of vasculopathy in diabetic patients.
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