Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hypoxia training attenuates left ventricular remodeling in rabbit with myocardial infarction.

Journal of geriatric cardiology : JGC·2014

Same author

Imides modified benzopicenes: synthesis, solid structure and optoelectronic properties.

Organic & biomolecular chemistry·2014

Same author

An efficient identity-based key management scheme for wireless sensor networks using the Bloom filter.

Sensors (Basel, Switzerland)·2014

Same author

A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.

Nature communications·2014

Same author

A new nodavirus is associated with covert mortality disease of shrimp.

The Journal of general virology·2014

Same author

Sensitive detection of trace amounts of KRAS codon 12 mutations by a fast and novel one-step technique.

Clinical biochemistry·2014

Search research articles

Related Experiment Video

Updated: Jul 10, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

Development of nano-hydroxyapatite coating by electrohydrodynamic atomization spraying.

Xiang Li¹, Jie Huang, Mohan Edirisinghe

¹Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK. xiang.li@ucl.ac.uk

Journal of Materials Science. Materials in Medicine

|November 10, 2007

Summary

Researchers optimized electrohydrodynamic atomisation (EHDA) spraying of nano-hydroxyapatite (nHA) to create high-quality, nanostructured HA coatings. Achieving a stable cone-jet mode is key for uniform, microstructurally sound coatings for biomedical uses.

More Related Videos

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Fabrication of Gradient Nanopattern by Thermal Nanoimprinting Technique and Screening of the Response of Human Endothelial Colony-forming Cells

Fabrication of Gradient Nanopattern by Thermal Nanoimprinting Technique and Screening of the Response of Human Endothelial Colony-forming Cells

Published on: July 1, 2018

Related Experiment Videos

Last Updated: Jul 10, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

Fabrication of Gradient Nanopattern by Thermal Nanoimprinting Technique and Screening of the Response of Human Endothelial Colony-forming Cells

Fabrication of Gradient Nanopattern by Thermal Nanoimprinting Technique and Screening of the Response of Human Endothelial Colony-forming Cells

Published on: July 1, 2018

Area of Science:

Materials Science
Biomedical Engineering
Nanotechnology

Background:

Hydroxyapatite (HA) coatings are crucial for biomedical implants due to their biocompatibility.
Electrohydrodynamic atomisation (EHDA) offers a promising method for creating nanostructured HA coatings.
Controlling EHDA processing parameters is essential for achieving desired coating morphology and quality.

Purpose of the Study:

To systematically investigate the influence of key processing parameters on EHDA spraying of nano-hydroxyapatite (nHA) suspensions.
To identify optimal conditions for producing uniform and structurally sound nHA coatings.
To advance the application of EHDA spraying for high-quality biomedical coatings.

Main Methods:

Utilized electrohydrodynamic atomisation (EHDA) to spray nano-hydroxyapatite (nHA) suspensions.
Varied key parameters: suspension flow rate, applied voltage, needle-substrate distance, and needle size.
Evaluated coating uniformity and microstructural integrity under different processing conditions.

Main Results:

All investigated parameters significantly influenced the morphology of the nHA coating.
Optimized conditions (300 µm needle, 20 mm distance, 20 µL/min flow rate, 4.3–5.2 kV) yielded a uniform nHA coating.
Stable cone-jet mode was critical for improving coating quality and morphology.

Conclusions:

EHDA spraying parameters critically affect nHA coating characteristics.
Optimized EHDA spraying provides a viable route for producing advanced, high-quality nano-hydroxyapatite coatings.
This work represents a significant advancement for nHA coatings in biomedical applications.