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Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

Treatment Resistant Cancers

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

Treatment Resistent Cancers

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Related Experiment Video

Updated: Jul 10, 2026

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

[Update on chemoinfusion and chemoembolization treatments].

A Lubienski¹, M Simon, K Lubienski

¹Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland. andreas.lubienski@uk-sh.de

|November 10, 2007

Summary

Image-guided regional therapies, including transarterial infusion chemotherapy (HAIC) and transarterial chemoembolization (TACE), offer revolutionary treatments for liver tumors. These methods deliver chemotherapy directly to tumors, minimizing systemic side effects for patients with liver cancer.

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Electrochemotherapy of Tumours

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Published on: December 15, 2008

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Last Updated: Jul 10, 2026

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

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Electrochemotherapy of Tumours

Electrochemotherapy of Tumours

Published on: December 15, 2008

Area of Science:

Interventional Radiology
Oncology
Hepatology

Background:

Image-guided interventional catheterizations and percutaneous ablative therapies have transformed nonresectable liver tumor treatment.
Treatments are categorized into chemoablative and thermo-/radioablative procedures.

Purpose of the Study:

To describe the role of chemoablative regional therapies in managing primary and secondary liver tumors.
To highlight transarterial infusion chemotherapy (HAIC) and transarterial chemoembolization (TACE) as key chemoablative interventions.

Main Methods:

Focuses on transarterial delivery of chemotherapy agents directly into liver tumors via hepatic arteries.
Aims to maximize intratumoral drug concentration while minimizing systemic drug exposure.

Main Results:

Transarterial treatments enable targeted delivery of chemotherapy to liver tumors.
These procedures are effective for hepatocellular carcinoma (HCC) and colorectal metastases.

Conclusions:

Transarterial chemoablative therapies represent a significant advancement in liver tumor treatment.
HAIC and TACE are crucial for managing HCC and secondary liver malignancies.