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Organ procurement in Singapore.

P Soh1, S M Lim, E C Tan

  • 1Department of Surgery, National University Hospital.

Annals of the Academy of Medicine, Singapore
|July 1, 1991
PubMed
Summary

Singapore

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Area of Science:

  • Nephrology
  • Transplant Surgery
  • Public Health Policy

Background:

  • Kidney transplantation in Singapore began in 1970.
  • Early transplant rates were low, averaging 4.7 cadaveric transplants annually until 1987.
  • Graft survival improved with the introduction of cyclosporine in 1985.

Purpose of the Study:

  • To analyze the impact of medical and legislative advancements on kidney transplantation rates in Singapore.
  • To evaluate the effectiveness of the Human Organ Transplant Act in increasing organ procurement.

Main Methods:

  • Retrospective analysis of kidney transplant data in Singapore from 1970 to 1990.
  • Examination of the correlation between the introduction of cyclosporine, transplant coordinator appointments, and the Human Organ Transplant Act with transplant volumes.

Main Results:

  • Kidney transplant rates significantly increased from 4.7 to 31.3 annually between 1988-1990.
  • The Human Organ Transplant Act (1987) was a major driver, accounting for over half of procured kidneys (55/94) during 1988-1990.
  • Full-time transplant coordinators appointed in 1986 also contributed to the increased rate.

Conclusions:

  • The combination of immunosuppressive therapy (cyclosporine), dedicated transplant coordination, and supportive legislation like the Human Organ Transplant Act dramatically improved kidney transplant activity in Singapore.
  • Legislative measures play a crucial role in enhancing organ donation and transplantation outcomes.

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