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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
Persistent viral infection in primary Sjogren's syndrome: review and perspectives
Antigoni Triantafyllopoulou1, Haralampos Moutsopoulos
1Division of Rheumatology, Hospital for Special Surgery, New York, NY, USA.
Abstract:
Exocrine gland pathology in primary Sjogren's syndrome is characterized by destruction of acinar epithelial cells and chronic lymphocytic infiltrates surrounding ductal epithelial cells. These cells seem to be activated, as it is inferred by their immunophenotype. The cause of this activation and the chronic inflammatory response that targets epithelial cells remain unknown. Here, we will review the evidence pointing to a persistent viral infection as a probable cause of primary Sjogren's syndrome and discuss potential directions for future research.
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