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Updated: Jul 10, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Studies on chemical constituents of in herb Pyrola calliatha]
Lei Liu1, Yu-ping Chen, Zhe Wan
1School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Objective:
To investigate the chemical constituents of Pyrola calliatha.
Method:
The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data.
Result:
Ten compounds were isolated and identified as chimaphilin (1), uvaol(2), ursolic acid (3), 2beta,3beta,23-trihydroxy-12-ene-28-ursolic acid (4), daucosterol (5), 2alpha,3beta,23,24-tetrahydroxy-12-ene-28-ursolic acid (6), emodin (7), gallic acid (8), monotropein (9), adenosine (10).
Conclusion:
Compounds 2,4,6,7,10 were obtained from this genus for the first time, compounds 5, 9 were obtained from this species for the first time. Antifungal activity of compounds 1-4, 6-9 were evaluated. Compound 1 showed the strong activity.