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Updated: Jul 10, 2026

An Epithelial Abrasion Model for Studying Corneal Wound Healing

An Epithelial Abrasion Model for Studying Corneal Wound Healing

Published on: December 29, 2021

Abnormal rubbing and keratectasia.

Charles W McMonnies¹

¹School of Optometry and Vision Science, University of New South Wales, Kensington, Australia. cmcmonnies@unsw.edu.au

Eye & Contact Lens

|November 13, 2007

Summary

Abnormal eye rubbing may cause or worsen keratoconus, a condition affecting corneal shape. This habit, especially vigorous rubbing, can increase the risk and progression of keratoconus and similar corneal conditions.

Area of Science:

Ophthalmology
Corneal Diseases
Pathogenesis

Background:

Keratoconus pathogenesis involves varied hypotheses.
The role of abnormal eye rubbing in keratoconus development and progression is explored.

Purpose of the Study:

To examine the possibility that abnormal rubbing causes or contributes to keratoconus.
To review evidence linking abnormal rubbing to keratoconus.

Main Methods:

Review of circumstantial evidence associating abnormal rubbing with keratoconus.
Description of various forms of abnormal rubbing.
Examination of mechanisms by which corneal rubbing trauma can cause adverse effects.

Main Results:

Inflammatory mediators may play a role in keratoconus pathogenesis.

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Last Updated: Jul 10, 2026

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Vigorous rubbing can subject the cornea to high intraocular pressure, potentially promoting ectasia.

Conclusions:

Abnormal rubbing is a likely cause of some keratoconus types by increasing susceptibility.
Rubbing habits, potentially exacerbated by contact lens wear, can contribute to keratoconus progression.
The rubbing-ectasia link may apply to other conditions, including post-LASIK keratectasia.