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Related Concept Videos

Morphogenesis02:19

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
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Cytokinesis segregates a cell’s chromosomes and organelles into its daughter cells. Organelles divide and grow prior to cell division but cannot be synthesized de novo; therefore, cells must receive at least one copy of each organelle to survive. Currently, many of the details of how the organelles are distributed are not yet fully elucidated.
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Related Experiment Video

Updated: Jun 20, 2026

Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

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Published on: May 8, 2015

Orchestrating size and shape during morphogenesis.

Thomas Lecuit1, Loïc Le Goff

  • 1Université de la Méditerranée, Institut de Biologie du Développement de Marseille Luminy (IBDML), Marseille Cedex 09, France. lecuit@ibdml.univ-mrs.fr

Nature
|November 13, 2007
PubMed
Summary
This summary is machine-generated.

Conserved developmental mechanisms guide organism diversity. Research in Drosophila reveals how signaling pathways and mechanical forces control tissue patterning, growth, and shape, integrating new models of size control.

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Area of Science:

  • Developmental biology
  • Cell biology
  • Biophysics

Background:

  • Organisms display vast diversity in form and size.
  • Conserved molecular mechanisms underlie development across species.
  • Drosophila melanogaster is a key model for studying developmental processes.

Purpose of the Study:

  • To identify conserved signaling pathways controlling tissue pattern formation.
  • To understand the regulation of tissue growth, shape, and coordination.
  • To integrate models of how signals and mechanical forces influence tissue development and size.

Main Methods:

  • Utilizing Drosophila as a model organism.
  • Investigating cellular and tissue-level coordination.
  • Analyzing signaling pathways involved in pattern formation.
  • Developing new models integrating mechanical forces and cellular signals.

Main Results:

  • Identified conserved mechanisms controlling organism development.
  • Elucidated signaling pathways crucial for tissue patterning.
  • Advanced understanding of cellular and tissue coordination in growth and shape.
  • Developed integrated models for tissue size control.

Conclusions:

  • Conserved developmental mechanisms explain organismal diversity.
  • Signaling pathways and mechanical forces are key regulators of tissue development.
  • Integrated models provide a framework for understanding tissue size control.