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How the excluded volume architecture influences ion-mediated forces between proteins

V Dahirel1, M Jardat, J-F Dufrêche

  • 1Laboratoire Liquides Ioniques et Interfaces Chargées, UMR CNRS 7612, Université Pierre et Marie Curie-Paris 6, case courrier 51, 4 place Jussieu F-75252, Paris Cedex 05, France.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|November 13, 2007
PubMed
Summary

Protein shape significantly impacts interactions, reducing electrostatic screening and enhancing binding affinity and selectivity. Monte Carlo simulations reveal how excluded volume architecture affects these forces.

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