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Updated: Jul 10, 2026

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages
Published on: June 2, 2020
Inferring genome-scale rearrangement phylogeny and ancestral gene order: a Drosophila case study
Arjun Bhutkar1, William M Gelbart, Temple F Smith
1BioMolecular Engineering Research Center, Boston University, Cummington St, Boston, MA 02215, USA. arjunb@morgan.harvard.edu
Abstract:
A simple, fast, and biologically inspired computational approach for inferring genome-scale rearrangement phylogeny and ancestral gene order has been developed. This has been applied to eight Drosophila genomes. Existing techniques are either limited to a few hundred markers or a small number of taxa. This analysis uses over 14,000 genomic loci and employs discrete elements consisting of pairs of homologous genetic elements. The results provide insight into evolutionary chromosomal dynamics and synteny analysis, and inform speciation studies.
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