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Updated: Jul 10, 2026

Murine Hind Limb Explant Model for Studying the Mechanobiology of Achilles Tendon Impingement
Published on: December 8, 2023
Noninsertional Achilles tendinopathy
Michael S Hennessy1, Andrew P Molloy, Simon W Sturdee
1Wirral Hospitals NHS Trust, Upton, Wirral, CH49 5PE, UK. mchenno@btinternet.com
Abstract:
The treatment of noninsertional Achilles tendinopathy remains, to a large extent, empirical. Neither different operative techniques nor nonoperative regimes have been subjected to controlled trials. Rather, the condition is still treated on the basis of anecdotal evidence combined with personal experience. However, increased knowledge of the basic science of tendinopathy and tendon healing has directed therapeutic regimens and will continue to do so. Manipulation of proteolytic enzymes and control of neovascularization are probably the two areas that show most promise.
