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Related Concept Videos

Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

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Related Experiment Video

Updated: Jul 10, 2026

Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations
05:49

Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations

Published on: October 26, 2011

Experimental hepatology applied to stem cells.

P Burra1, S Tomat, E Villa

  • 1Department of Surgical and Gastroenterological Sciences, University of Padua, Italy. burra@unipd.it

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
|November 13, 2007
PubMed
Summary

Organ transplantation faces challenges due to donor shortages. Research explores alternatives like stem cells and xenotransplantation to address organ failure and improve patient outcomes.

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Area of Science:

  • Regenerative Medicine
  • Transplantation Biology
  • Cell Therapy

Background:

  • Organ transplantation is a vital treatment for organ failure.
  • Increasing patient numbers and limited organ donors create long waiting lists.
  • Alternative strategies are crucial to meet the growing demand for organs.

Purpose of the Study:

  • To summarize recent advancements in organ support and transplantation alternatives.
  • To consolidate findings from a conference on stem cells and xenotransplantation.
  • To provide a comprehensive overview of stem cell research and gene therapy applications.

Main Methods:

  • Review of a Single-Topic Conference sponsored by AISF.
  • Analysis of discussions on stem cell biology and gene therapy.
  • Integration of perspectives from clinicians and scientists across multiple specialties.

Main Results:

  • Exploration of bio-artificial support devices and cell transplantation.
  • Investigation into the potential of xenotransplantation for organ replacement.
  • Discussion of gene therapy as a potential treatment modality.

Conclusions:

  • Stem cell research and xenotransplantation show promise for addressing organ shortages.
  • Interdisciplinary collaboration is key to advancing transplantation alternatives.
  • Continued research is essential to overcome current limitations in organ replacement therapies.