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Receptor mosaics of neural and immune communication: possible implications for basal ganglia functions
Luigi F Agnati1, Kjell G Fuxe, Larisa B Goncharova
1Department of Biomedical Sciences, University of Modena and Reggio Emilia, Italy.
Abstract:
Receptor assemblies seem to play a key role in the integration and modulation of molecular signals of cell-cell communications. This may be confirmed by recent discoveries of the immunological synapse and cytokine networks which can be also treated within a sort of meta-system-neuroimmune molecular network. On the examples of receptor superfamilies expressed both in the neural and immune cells, our review paper aims to show some implications of receptor-receptor interactions for basal ganglia functions in health and disease.
