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Multilevel infusion catheter for use with thrombolytic agents
M E Hicks1, D Picus, M D Darcy
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110.
Journal of Vascular and Interventional Radiology : JVIR
|February 1, 1991
Summary
A novel multilevel infusion catheter ensures equal flow distribution for thrombolytic agents. This new device achieved complete thrombolysis in all 20 peripheral vascular occlusion cases treated.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Biomedical Engineering
Background:
- Peripheral vascular occlusions pose significant treatment challenges.
- Effective delivery of thrombolytic agents is crucial for successful treatment.
- Existing infusion catheters may have limitations in flow distribution and positioning.
Purpose of the Study:
- To describe a new multilevel infusion catheter designed for enhanced thrombolytic agent delivery.
- To evaluate the catheter's performance in achieving equal flow distribution.
- To assess the efficacy of the catheter in treating peripheral vascular occlusions.
Main Methods:
- A novel 4.7 F multilevel infusion catheter with four infusion ports was developed.
- The catheter features fluoroscopically visible length markers for precise positioning.
- The catheter was used for urokinase infusion in 20 patients with peripheral vascular occlusions.
Main Results:
- The catheter demonstrated near-equal flow distribution through all four infusion ports.
- Secure positioning within the occluded vessel segment was achieved.
- Complete or near-complete thrombolysis was observed in all 20 treated cases.
Conclusions:
- The new multilevel infusion catheter offers advantages in flow distribution and positioning.
- It is an effective tool for delivering thrombolytic agents in peripheral vascular occlusions.
- This catheter facilitates successful thrombolysis, improving patient outcomes.