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Related Experiment Videos

RI Manager, a microcomputer program for analysis of data from recombinant inbred strains.

K F Manly1, R W Elliott

  • 1Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, New York 14263.

Mammalian Genome : Official Journal of the International Mammalian Genome Society
|January 1, 1991
PubMed
Summary

RI Manager software aids genetic mapping by analyzing recombinant inbred strain data. It quickly finds genetic linkage and optimizes gene mapping orders for researchers.

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Area of Science:

  • Genetics
  • Bioinformatics
  • Computational Biology

Background:

  • Genetic mapping relies on analyzing data from recombinant inbred strains.
  • Efficient storage and analysis tools are crucial for genetic mapping studies.

Purpose of the Study:

  • To introduce RI Manager, a microcomputer program for genetic mapping data.
  • To enable rapid identification of genetic linkage and evaluation of map orders.

Main Methods:

  • Utilized a microcomputer program (RI Manager) for data management.
  • Employed statistical analysis to identify linkage between genetic loci.
  • Facilitated the evaluation of alternative mapping orders.

Main Results:

  • RI Manager efficiently stores and analyzes genetic mapping data.

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  • The program rapidly identifies statistically significant linkage between loci.
  • Alternative map orders for linked loci can be rapidly evaluated.

    • Conclusions:

    • RI Manager is a valuable tool for genetic mapping research.
    • The software streamlines the analysis of recombinant inbred strain data.
    • It accelerates the process of genetic linkage identification and map construction.