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Mutant Chlamydia trachomatis in Denmark.

Steen Hoffmann1, J S Jensen

  • 1Department of Bacteriology, Mycology, and Parasitology, Statens Serum Institut, Copenhagen, Denmark. hof@ssi.dk

Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
|November 14, 2007
PubMed
Summary
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A new Chlamydia trachomatis variant, first seen in Sweden, was found in one Danish woman in 2007. Its spread into and within Denmark appears unexpectedly low compared to Sweden.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • A novel Chlamydia trachomatis variant emerged in Sweden in 2006.
  • This variant has since been identified in Norway, but not Ireland or the Netherlands.
  • The geographical spread and prevalence of this sexually transmitted infection variant require investigation.

Purpose of the Study:

  • To determine the presence of the new Chlamydia trachomatis variant in Denmark.
  • To assess the early dissemination of this variant within the Danish population.

Main Methods:

  • Testing of 3,770 specimens collected between November 2006 and April 2007.
  • Utilizing specific diagnostic methods to detect the new variant and differentiate it from the wild-type Chlamydia trachomatis.

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  • Case identification and epidemiological linkage analysis.

    • Main Results:

    • One case of the new Chlamydia trachomatis variant was identified in a 19-year-old Danish woman in late March 2007.
    • The identified case had no known direct link to Sweden.
    • The prevalence and spread of the variant in Denmark appeared limited during the study period.

    Conclusions:

    • The new Chlamydia trachomatis variant has been introduced into Denmark.
    • The observed low prevalence and limited spread suggest a slower initial dissemination compared to Sweden.
    • Further surveillance is warranted to monitor the ongoing spread of this Chlamydia trachomatis variant in Denmark.