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Updated: Jul 10, 2026

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

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Published on: November 21, 2025

Good agreement between physician and self-reported hormone therapy data in a case-control study.

S Kropp¹, T Terboven, J Hedicke

¹Department of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany. s.kropp@dkfz.de

Journal of Clinical Epidemiology

|November 14, 2007

Summary

Self-reported postmenopausal hormone therapy (HT) use accurately reflects physician records, showing good agreement for ever/never use and duration. This validates patient recall for HT use in epidemiological studies.

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Last Updated: Jul 10, 2026

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Published on: November 21, 2025

Area of Science:

Reproductive Medicine
Epidemiology
Pharmacovigilance

Background:

Accurate assessment of postmenopausal hormone therapy (HT) use is crucial for understanding its effects on breast cancer risk.
Validation studies are essential to confirm the reliability of self-reported data against objective sources like prescription records.

Purpose of the Study:

To validate self-reported postmenopausal hormone therapy (HT) use against physician prescription data in a population-based case-control study.
To assess the agreement between patient recall and medical records for various aspects of HT use, including type, duration, and timing.

Main Methods:

A validation sub-study was conducted within a population-based case-control study in Germany (2002-2005).
224 cases and 225 controls were randomly selected and stratified by region, age, and hormone use.
Comparison involved matching self-reported HT data with gynecologists' prescription records.

Main Results:

High agreement was observed for ever/never HT use (88.2%) and by specific types of HT (80.3%-90.5%).
Intraclass correlation coefficients indicated high reliability for duration of use (0.82) and age at first/last use (0.88-0.98).
Agreement on exact brand names was moderate (50.2% perfect, 29.3% partial), but overall agreement was not influenced by disease status.

Conclusions:

Self-reported postmenopausal hormone therapy (HT) data demonstrated substantial concordance with physician prescription records.
The findings support the use of self-reported HT information in epidemiological research, particularly for assessing general use and duration.
High reliability in reporting HT use enhances the validity of studies investigating its association with health outcomes like breast cancer.