Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vasopressor support in septic shock.

Steven M Hollenberg1

  • 1Robert Wood Johnson Medical School/University of Medicine and Dentistry of New Jersey, Cooper University Hospital, Camden, NJ 08103, USA. Hollenberg-Steven@cooperhealth.edu

Chest
|November 14, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

THE SOCIETY OF CRITICAL CARE CARDIOLOGY - RATIONALE, BLUEPRINT, AND LESSONS LEARNED IN THE CREATION OF A NEW MULTIDISCIPLINARY PROFESSIONAL ORGANIZATION.

American heart journal·2026
Same author

Septic cardiomyopathy: a form of myocardial hibernation?

European heart journal·2025
Same author

The Heart in Overdrive, the Mind in Doubt.

Critical care medicine·2025
Same author

Association of noradrenaline dose with mortality in critically ill patients: a systematic review and dose-response meta-analysis.

Critical care (London, England)·2025
Same author

Reversible Myocardial Depression and Dilatation in COVID-19 Shock Patients.

Critical care explorations·2025
Same author

Cardiac patients in intensive care unit research: an urgent call for inclusion.

European heart journal. Acute cardiovascular care·2025
Same journal

A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

Chest·2026
Same journal

Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

Chest·2026
Same journal

Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

Chest·2026
Same journal

Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

Chest·2026
Same journal

Symptom prevalence and impact on lung cancer risk in the SUMMIT study.

Chest·2026
Same journal

How I Do It: De-escalation of Prostacyclin-Based Therapy in Patients Treated With Sotatercept.

Chest·2026
See all related articles

In septic shock, vasopressor agents are crucial when fluids fail. Therapy aims to restore blood pressure and organ perfusion, but optimal targets vary, emphasizing individualized treatment strategies.

Area of Science:

  • Critical Care Medicine
  • Pharmacology
  • Physiology

Background:

  • Septic shock management requires vasopressor therapy when fluid resuscitation is insufficient.
  • Effective tissue perfusion and normalized cellular metabolism are key goals in shock treatment.

Purpose of the Study:

  • To discuss the strategic selection of vasopressor agents in septic shock.
  • To highlight the importance of individualized blood pressure targets and hemodynamic monitoring.

Main Methods:

  • Review of current understanding of vasopressor use in septic shock.
  • Analysis of the relationship between arterial pressure, blood flow, and organ perfusion.
  • Emphasis on monitoring clinical and hemodynamic parameters to guide therapy.

Related Experiment Videos

Main Results:

  • Arterial pressure is an endpoint, but not always equivalent to blood flow; precise BP goals vary among patients.
  • Different vasopressor agents have distinct effects on pressure and flow, influencing therapeutic strategy.
  • Optimizing regional and microcirculatory blood flow remains an area of uncertainty.

Conclusions:

  • Hemodynamic support in sepsis should consider both pressure and perfusion.
  • Therapeutic efficacy requires ongoing assessment using combined clinical and hemodynamic parameters.
  • Defining specific, individualized goals and endpoints for vasopressor therapy is a fundamental principle.