Related Experiment Video
Updated: Jul 10, 2026
06:42
Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
Breast cancer in males: a PGIMER experience.
Bhavana Rai1, Sushmita Ghoshal, Suresh C Sharma
1Department of Radiotherapy, Post Grade Institute of Medical Education and Research, Chandigarh, India.
Journal of Cancer Research and Therapeutics
|November 14, 2007
Summary
This study on male breast cancer found a 40% five-year disease-free survival rate. Advanced disease at presentation was linked to loco-regional recurrence and distant metastasis in male breast cancer patients.
Area of Science:
- Oncology
- Medical Research
Background:
- Male breast cancer is a rare malignancy, accounting for 1% of all breast cancers.
- Limited research exists due to its rarity, necessitating further investigation into clinical and pathological aspects.
Purpose of the Study:
- To analyze clinical and pathological features of male breast cancer.
- To evaluate prognostic factors influencing outcomes.
- To correlate patient outcomes with disease characteristics.
Main Methods:
- Retrospective analysis of 30 male breast cancer patients treated between 1996 and 2000.
- Data collected from the department of radiotherapy.
Main Results:
- Actuarial five-year disease-free survival was 40%.
- 10% of patients experienced loco-regional recurrence, all with locally advanced disease.
- Distant metastasis occurred in 9 patients, with a higher incidence in T3-T4 tumors.
Conclusions:
- Modified radical mastectomy and radiation therapy are standard treatments.
- Adjuvant hormone therapy is a primary approach; chemotherapy is reserved for poor prognostic cases.
Related Concept Videos
01:20Disorders of the Male Reproductive System
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
01:24Disorders of the Female Reproductive System
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
02:18Cancer
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
01:23Infertility in Males
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...