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Updated: Jul 10, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Squamous cell carcinoma over a nevus: a rare case
K C Patro1, S Padhi, D N Singh
1Acharya Harihar Regional Cancer Centre, Cuttack, Orissa, India. kanhu66@yahoo.co.uk
Squamous cell carcinoma developing over a nevus is rare. This case highlights a 55-year-old male with scalp squamous cell carcinoma arising from a nevus, treated with surgery and radiotherapy.
Area of Science:
- Dermatology
- Oncology
Background:
- Malignant melanoma and basal cell carcinoma frequently arise from nevi.
- Squamous cell carcinoma developing from a nevus is an uncommon occurrence.
Observation:
- A 55-year-old male presented with a slow-growing, noduloulcerative lesion on his scalp, originating from a preexisting nevus.
- Excisional biopsy confirmed the lesion as squamous cell carcinoma with positive lateral margins.
Findings:
- The patient received postoperative high-dose-rate (HDR) brachytherapy for the confirmed squamous cell carcinoma.
- The tumor was successfully excised, with radiotherapy addressing the positive margins.
Implications:
- This case underscores the importance of vigilance for squamous cell carcinoma in nevi, despite its rarity.
- Early detection and multimodal treatment, including radiotherapy, are crucial for managing this rare oncological presentation.
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