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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Pharmacotherapy of asthma
1Department of Pharmaceutical Sciences, South University School of Pharmacy, Savannah, GA 31406, USA. mzdanowicz@southuniversity.edu
American Journal of Pharmaceutical Education
|November 14, 2007
Summary
Understanding asthma pharmacotherapy requires grasping its complex pathophysiology and the medicinal chemistry of various treatment drugs. This review details asthma drug classes, mechanisms, and interactions to guide rational drug choices.
Area of Science:
- Pharmacology
- Medicinal Chemistry
- Pathophysiology
Background:
- Asthma pharmacotherapy is complex and evolving.
- Understanding pathophysiology is key to drug action.
- Knowledge of drug chemistry and properties guides treatment.
Purpose of the Study:
- To provide a synopsis of asthma pathophysiology and pharmacology.
- To detail various classes of asthma drugs.
- To prepare students for asthma therapeutics.
Main Methods:
- Review of pertinent pathophysiology.
- Detailed presentation of asthma drug classes.
- Discussion of drug chemistry, mechanism of action, pharmacokinetics, toxicity, and interactions.
Main Results:
- Synopsis covers asthma pathophysiology.
- Detailed presentation covers drug classes, chemistry, MOA, PK, toxicity, and interactions.
- Content emphasizes complexities, controversies, and future drug development.
Conclusions:
- A solid comprehension of asthma pathophysiology and drug properties is critical for effective pharmacotherapy.
- This review prepares students for advanced asthma therapeutics.
- Understanding drug mechanisms and interactions aids in rational drug selection and minimizing side effects.
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