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Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Motor Unit Stimulation01:20

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
Tetanus01:29

Tetanus

Tetanus is a life-threatening neurological disorder characterized by persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. These bacteria produce terminal endospores, giving them a distinctive “lollipop” or “tennis-racket” appearance. They thrive in anaerobic environments, such as those found in deep puncture wounds.Once introduced into the body, the spores germinate into vegetative cells. These cells...
Isotonic and Isometric Muscle Contractions01:22

Isotonic and Isometric Muscle Contractions

Two primary types of muscle contractions are isotonic and isometric, each serving unique functions and involving distinct mechanisms. Both isotonic and isometric contractions are integral to the body's complex system of movement and stability. Isotonic exercises contribute significantly to functional strength and movement, while isometric contractions are crucial for maintaining posture and joint stability.
Isotonic contractions
Isotonic contractions occur when a muscle changes length while the...

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Related Experiment Video

Updated: Jul 10, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Action-induced clonus mimicking tremor.

Valérie Fraix1, Isabelle Delalande, Marianne Parrache

  • 1Department of Clinical Neurophysiology, Salengro Hospital, Lille University Hospital, Lille, France.

Movement Disorders : Official Journal of the Movement Disorder Society
|November 14, 2007
PubMed
Summary

This study suggests that prolonged action-induced clonus, not typically recognized as action tremor, may occur after central motor pathway lesions. These findings highlight a potential mimic of action tremor in neurological conditions.

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Corticospinal Excitability Modulation During Action Observation
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Corticospinal Excitability Modulation During Action Observation

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MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
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MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

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Related Experiment Videos

Last Updated: Jul 10, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Corticospinal Excitability Modulation During Action Observation
12:33

Corticospinal Excitability Modulation During Action Observation

Published on: December 31, 2013

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

Area of Science:

  • Neurology
  • Neuroscience
  • Movement Disorders

Background:

  • Action tremor is a complex motor symptom with diverse etiologies, including cerebellar, task-specific, dystonic, and Holmes tremor.
  • Understanding the pathophysiology of action tremor is crucial for accurate diagnosis and effective treatment.

Observation:

  • Two patients presented with unilateral kinetic or isometric action tremor of the upper extremity after experiencing cervical spondylotic myelopathy and capsular ischemic stroke.
  • Affected limbs exhibited mild motor weakness, spasticity, exaggerated tendon jerks, and passive stretch-induced clonus.

Findings:

  • Central motor pathway lesions may lead to stretch-reflex arc hyperexcitability and enhanced skeletal muscle coactivation due to impaired descending or segmental spinal reflex control.
  • The study hypothesizes that prolonged action-induced clonus, mimicking action tremor, resulted from these central lesions.

Implications:

  • This research suggests that action tremor can manifest as prolonged action-induced clonus under specific conditions involving central motor pathway damage.
  • Recognizing this phenomenon is vital for differentiating true action tremor from clonus-induced symptoms in patients with neurological deficits.