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Ensembl 2008
1European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. flicek@ebi.ac.uk
Nucleic Acids Research
|November 15, 2007
Summary
The Ensembl project provides comprehensive genome annotation and databases for 35 species, including new additions like platypus and horse. Recent updates enhance functional genomics data, user customization, and genome resequencing capabilities.
Area of Science:
- Bioinformatics
- Genomics
- Comparative Genomics
Background:
- The Ensembl project is a major genome information system.
- It provides integrated genome annotation and databases for various species.
Purpose of the Study:
- To report on the latest developments and expansions of the Ensembl project.
- To highlight new features supporting functional genomics, comparative genomics, and user customization.
Main Methods:
- Expansion of species support to 35 fully supported and 6 preliminarily supported genomes.
- Integration of functional genomics data, including protein-DNA interactions and regulatory builds.
- Development of user accounts and groups for web interface customization.
- Enhancements in comparative genomics data mining and genome resequencing support.
Main Results:
- Ensembl now supports 35 species, with recent additions of platypus and horse.
- New functional genomics database and regulatory build provide extensive data.
- User accounts and groups enable customized Ensembl web interface.
- Improved support for genome resequencing and comparative genomics data mining.
Conclusions:
- The Ensembl project continues to expand its scope and features.
- Recent updates significantly enhance its utility for functional genomics, comparative analysis, and user-specific research.
- Ongoing development of software infrastructure ensures continued advancement.
