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TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

Bernhard Schmierer1, Caroline S Hill

  • 1Developmental Signalling Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.

Nature Reviews. Molecular Cell Biology
|November 15, 2007
PubMed
Summary

Transforming growth factor-beta (TGFbeta) signaling involves complex ligand-receptor interactions. Research explores how signal strength and duration regulate SMAD activity for cell-specific responses.

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