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Published on: February 1, 2018
Cancer in Appalachia, 2001-2003
Phyllis A Wingo1, Thomas C Tucker, Patricia M Jamison
1Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Cancer incidence rates are higher in Appalachia than the US, with significant regional variations. Lung, colon, and tobacco-related cancer rates are particularly elevated across the Appalachian region.
Area of Science:
- Epidemiology
- Public Health
- Cancer Research
Background:
- Cancer incidence data in Appalachia were previously limited due to inconsistent high-quality registry availability.
- This study addresses this gap by providing cancer incidence rates for a significant portion of the Appalachian population.
Purpose of the Study:
- To report cancer incidence rates across Appalachia.
- To examine and describe variations in cancer incidence between Northern, Central, and Southern Appalachian regions.
Main Methods:
- Utilized high-quality cancer registry data from 44 states and DC for diagnosis years 2001-2003.
- Included 11 of 13 Appalachian states (88% of the population); Virginia and Mississippi included for 2003 only.
- Calculated age-adjusted incidence rates per 100,000 population using SEER(*)Stat software.
Main Results:
- Overall cancer incidence rates in Appalachia exceeded those in the rest of the US.
- Elevated rates observed for lung, colon/rectum, and other tobacco-related cancers.
- Central Appalachia showed the highest lung and cervical cancer rates; Northern Appalachia had the highest prostate and female breast cancer rates.
Conclusions:
- Appalachia exhibits higher cancer incidence rates compared to the broader US, with notable regional disparities.
- Further research is essential to investigate the links between lifestyle, socioeconomic status, urban/rural factors, and healthcare access and these observed cancer rate variations within Appalachia.
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