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Sleep Apnea

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Updated: Jul 10, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

[Association between severe obstructive sleep apnea syndrome and sinus dysfunction].

Hao Wang¹, Xi-long Zhang, Yu-ying Cai

¹Department of Respiratory Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Zhonghua Yi Xue Za Zhi

|November 16, 2007

Summary

Patients with severe obstructive sleep apnea syndrome (OSAS) have a higher incidence of sinus dysfunction (SD) compared to simple snorers. Lowering of Nadir pulse oxygen saturation during sleep is a primary risk factor for developing SD in severe OSAS patients.

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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Area of Science:

Cardiology
Pulmonology
Sleep Medicine

Context:

Obstructive sleep apnea syndrome (OSAS) is a prevalent condition characterized by recurrent upper airway collapse during sleep.
Sinus dysfunction (SD) can significantly impact quality of life and cardiovascular health.
The relationship between severe OSAS and SD requires further elucidation.

Purpose:

To investigate the preliminary association between severe obstructive sleep apnea syndrome (OSAS) and sinus dysfunction (SD).
To compare sinus function between patients with severe OSAS and simple snorers.
To identify risk factors for SD in patients with severe OSAS.

Summary:

A study involving 70 severe OSAS patients and 36 simple snorers revealed a significantly higher incidence of SD in the OSAS group (22.9% vs. 5.6%).
Nadir pulse oxygen saturation, longest apnea duration, and coronary artery disease incidence were significantly different between OSAS patients with and without SD.
Logistic regression identified decreased Nadir pulse oxygen saturation and age as key risk factors for SD in severe OSAS.

Impact:

This research highlights a critical link between severe OSAS and increased risk of sinus dysfunction.
Findings suggest that monitoring and managing oxygen saturation levels in OSAS patients may help mitigate the risk of SD.
The study provides a foundation for further research into the pathophysiological mechanisms connecting OSAS and SD.