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Updated: Jul 10, 2026

Infinium Assay for Large-scale SNP Genotyping Applications
Published on: November 19, 2013
Clustering of individuals given SNPs similarity based on normalized mutual information: F7 SNPs in the GAIT sample
Alexandre Perera1, Alfonso Buil, Maria Chiara Di Bernardo
1Centre de Recerca en Enginyeria Biomedica, Dept. d'Eng. Sistemes i Automatica Industrial, Universitat Politecnica de Catalunya, Pau Gargallo, 5, 08028 Barcelona, Spain. alexandre.perera@upc.edu
Abstract:
This paper proposes the clustering of individuals given their genotype using a normalized Mutual Information dissimilarity distance. This method is applied to a Single Nucleotyde Polymorphism set belonging to F7 gene, uncovering the intrinsic genetic variability on one Spanish population. This genetic variability corresponds to results published using a complete different approach in population genetics literature. Identified groups are shown to express significant differences in the level of FVII concentration.
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