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Updated: Jul 10, 2026

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
Hyperthermia system with thermoseed set in abdominal cavity and AC-magnetic-field
Kaori Abe1, Naruhiro Shiozawa, Msaaki Makikawa
1Graduate School of Science and Engineering, Ritsumeikan University, Shiga, Japan. rr000036@ritsumiekan.ac.jp
Abstract:
We propose a hyperthermia system for cancer developed in abdominal cavity. Local/deep spot heating and its less invasion feature are expected to be realized by thermoseed. This thermoseed is made of ferromagnetic material and it changes AC magnetic field power from outside of body to heat. AC magnetic field frequency is set on the value not to be absorbed to organs or tissues. We made a heat model of thermoseed and in vivo environment. The amount of heat and heat conduction were calculated from the characteristic values of materials and AC magnetic field. Effective shape of thermoseed for hyperthermia can be designed easily from this calculation. Results showed possibility of effective hyperthermia using this system through evaluation experiments.
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