Investigating new BioMEMS techniques for early detection of osteoporosis

Osteoporosis is a bone disease which requires early detection. The biomarkers provide a promising challenge of clinical proteomics for early disease detection. Different techniques like BMD testing, optical and electrochemical testing have been studied comparatively. New peaks have been identified in UV-visible spectroscopy at 420nm and high sensitivity is achieved by electrochemical technique with ng/ml to pico/ml level detection of bonemarkers. An electrochemical technique is found to be the best suitable for developing a new bioMEMS chip.