Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cerebral Edema l: Introduction

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Centering Equity During Health Technology Innovation: Scoping Review of Methods and Research Adjustments to Promote Inclusive Coproduction.

Journal of medical Internet research·2026

Same author

Concurrent Calcium Pyrophosphate Deposition Disease and Gout of the Cervical Spine Presenting With Subacute Neck Pain and Radiculopathy.

The Journal of rheumatology·2026

Same author

Pressure-activated disassembly of cryoprotectant supramolecules in isochoric freezing.

Cryobiology·2026

Same author

Fertility preservation trends, perspectives, and reflections in gender diverse adults across the life course.

Human reproduction (Oxford, England)·2026

Same author

Thermodynamic analysis of a partial freezing organ preservation protocol.

Cryobiology·2026

Same author

Label-free DNA-sensor modelling based on magnetic induction spectroscopy.

BioTechniques·2026

Search research articles

Related Experiment Video

Updated: Jul 10, 2026

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging

Published on: June 8, 2017

Inductive phase shift spectroscopy for volumetric brain edema detection: an experimental simulation.

César A González¹, Rafael Rojas, Cleva Villanueva

¹Universidad del Ejército y Fuerza Aérea, EMGS Lab. Mult. Invest., México, DF 11620, México. c.cesar.gonzalez@gmail.com

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

|November 16, 2007

Summary

This study explores a new non-invasive method using induction coils to detect fluid volume changes for brain edema monitoring. The technique shows promise for practical, non-invasive volumetric brain edema assessment.

More Related Videos

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Published on: May 7, 2017

Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space

Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space

Published on: July 24, 2017

Related Experiment Videos

Last Updated: Jul 10, 2026

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging

Published on: June 8, 2017

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Published on: May 7, 2017

Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space

Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space

Published on: July 24, 2017

Area of Science:

Biomedical Engineering
Medical Physics
Neuroscience

Background:

Brain edema monitoring is crucial for neurological conditions.
Current methods for volumetric brain edema assessment can be invasive or lack precision.
Developing non-invasive techniques is a significant goal in neurocritical care.

Purpose of the Study:

To experimentally evaluate an induction-based non-invasive technique for detecting fluid volume changes.
To assess the feasibility of using phase shift measurements for volumetric brain edema monitoring.
To investigate the relationship between fluid volume, frequency, and phase shift in a simulated head model.

Main Methods:

Construction of a two-compartment spherical head model with induction coils.
Simulation of varying brain edema levels using different volumes of physiological saline.
Measurement of phase shift of impedance coils at multiple frequencies (40-300 MHz) using a vector network analyzer.

Main Results:

A significant increase in phase shift was observed as a function of both frequency and fluid volume.
The induction coil-spherical head system demonstrated sensitivity to fluid volume changes.
Phase shift measurements correlated with simulated edema levels.

Conclusions:

The tested induction-based technique shows potential for non-invasive volumetric brain edema monitoring.
Phase shift measurements offer a viable approach for detecting changes in fluid volume.
Further development could lead to a practical clinical tool for brain edema assessment.