Propagation route estimation of heart sound through simultaneous multi-site recording on the chest wall

While vibration source of the heart sound has been well-studied, the propagation route of the heart sound on the chest wall has not been clarified. In this study, we first measured the heat sound simultaneously at 64 positions on the chest wall of healthy subjects using 64 small accelerometers. We next calculated the delay times in the vibration propagation between all possible pair of neighboring positions. We proposed the estimation method for the propagation route of heart sound vibration on the chest wall by solving the shortest path problem in the graph-network theory only using such neighboring delay times. Applying to the recorded heart sound signals, we can obtain the estimated propagation route originated at the cardiac apex for the first heart sound, and that originated at aortic valve for the second heart sound.