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Updated: Jul 10, 2026

A Computational Modeling Approach to Investigate the Influence of Hyperthermia on the Tumor Microenvironment
Published on: December 1, 2023
Heating properties of re-entrant resonant applicator for brain tumor by electromagnetic heating modes
1Department of Mechanical Engineering Informatics, Meiji University, Kawasaki, Japan. ce77234@isc.meiji.ac.jp
Abstract:
This paper discusses a new method to control the heating area of a re-entrant resonant cavity applicator for brain tumor hyperthermia treatment non-invasively. We have already discussed about the effectiveness of a developed system with experiments of heating an agar phantom and computer simulations. Here, in order to heat a deep brain tumor, we propose the heating method of using several electromagnetic heating modes which are transverse magnetic (TM) modes. In this method, TM010-like and TM012-like modes obtained by selecting resonant frequencies can be used to heat the deep brain tumors. To control the heating area of the modes the agar phantom is used in the heating experiments by the developed system. From these results, we found that the heating area of the agar phantom by using TM012-like mode is about 50% of the heating area of TM010-like mode. It is found that the proposed heating system can be applicable to the hyperthermia treatment of brain tumors corresponding to the size and the position where it occurred.
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