Related Experiment Video
Updated: Jul 10, 2026
Isolation of Human Mesenchymal Stem Cells and their Cultivation on the Porous Bone Matrix
Published on: February 9, 2015
Enhanced in vitro culture of human SAOS-2 osteoblasts on a sand-blasted titanium surface modified with plastic
Lorenzo Fassina1, Enrica Saino, Livia Visai
1University of Pavia, Dipartimento di Informatica e Sistemistica, Centro di Ingegneria Tissutale (C.I.T.), via Ferrata 1, 27100 Pavia, Italy. lorenzo.fassina@unipv.it
Abstract:
The titanium surfaces with micro-roughness have been studied to substitute machined titanium, with the focus on enhancing the bone apposition onto the implant. In this study we have followed a biomimetic strategy where human SAOS-2 osteoblasts proliferated and built their extracellular matrix on a sandblasted titanium surface modified with plastic deformation. In comparison with sandblasted titanium surface, the plastic deformation increased the cell proliferation and the surface coating with bone matrix. The superficially modified biomaterial could be used, in clinical applications, as an implant for bone repair.
More Related Videos
09:35Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
08:52Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
Published on: June 13, 2018