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Updated: Jul 10, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Association between psychiatric symptoms and erectile dysfunction.

Giovanni Corona¹, Valdo Ricca, Elisa Bandini

¹Andrology Unit, Department of Clinical Physiopathology, University of Florence, Italy.

The Journal of Sexual Medicine

|November 17, 2007

Summary

Erectile dysfunction (ED) is linked to various psychiatric symptoms, impacting organic, relational, and intrapsychic domains. Early detection through questionnaires can help manage these complex associations.

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Last Updated: Jul 10, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

Psychiatry
Urology
Psychology

Background:

Erectile dysfunction (ED) frequently co-occurs with diverse psychiatric symptoms.
Limited research systematically explores the specific links between ED determinants and these psychiatric conditions.

Purpose of the Study:

To investigate the association between erectile dysfunction (ED) and various psychopathological symptoms.
To quantify the contribution of organic, relational, and intrapsychic domains to ED using the SIEDY Structured Interview.
To screen for mental disorders in non-psychiatric settings using the Middlesex Hospital Questionnaire.

Main Methods:

A cohort of 1,388 male patients with ED (mean age 51 years) was studied.
Participants completed the SIEDY Structured Interview and the Middlesex Hospital Questionnaire.
Hormonal, biochemical, and sexual function parameters were assessed.

Main Results:

Psychiatric symptoms showed distinct associations with ED domains: depressive and phobic-anxiety symptoms linked to the relational domain; somatization to the organic domain; free-floating anxiety, obsessive-compulsive, and phobic symptoms to the intrapsychic domain.
Depressive symptoms correlated with hypogonadism, low intercourse frequency, hypoactive sexual desire (HSD), and relationship conflicts.
Somatization symptoms were associated with poorer erectile function, while phobic and obsessive-compulsive symptoms related to better relational functioning and lower HSD prevalence.

Conclusions:

Findings challenge the belief that psychiatric symptoms are uncommon in ED patients.
Systematic screening for psychopathological distress in ED patients is recommended.
Early detection and management of associated psychiatric issues can mitigate sexual disturbances.