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Related Experiment Videos

Bacteremia in hospitalized children.

P D Winchester, J K Todd, M H Roe

    American Journal of Diseases of Children (1960)
    |July 1, 1977
    PubMed
    Summary

    In hospitalized children, bacteremia (blood infection) was confirmed in 189 cases. Rapid diagnostic methods significantly altered treatment for nearly half of these pediatric bacteremia patients.

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    Area of Science:

    • Pediatric Infectious Diseases
    • Clinical Microbiology
    • Hospital Epidemiology

    Background:

    • Blood cultures are crucial for diagnosing bloodstream infections in children.
    • Understanding the epidemiology of pediatric bacteremia is essential for effective treatment.
    • Identifying common pathogens guides empirical antibiotic therapy.

    Purpose of the Study:

    • To review the results of blood cultures in hospitalized children.
    • To identify the prevalence and common causative organisms of pediatric bacteremia.
    • To assess the impact of rapid diagnostic techniques on patient management.

    Main Methods:

    • Retrospective review of 6,951 blood cultures from hospitalized children.
    • Analysis of organism growth and identification of confirmed bacteremia cases.
    • Evaluation of changes in patient therapy based on rapid diagnostic results.

    Main Results:

    • One or more organisms grew in 6% of cultures (399/6951).
    • Confirmed bacteremia was identified in 189 patients.
    • Common pathogens included Haemophilus influenzae, Streptococcus pneumoniae, Enterobacteriaceae, and Staphylococcus aureus.
    • Higher mortality was observed in immunocompromised children (neonates, oncology patients).
    • Rapid detection altered therapy in nearly 50% of bacteremic patients.

    Conclusions:

    • Pediatric bacteremia is associated with significant morbidity, particularly in vulnerable populations.
    • Prompt identification of pathogens through blood cultures is critical for timely therapeutic adjustments.
    • Advancements in laboratory diagnostics substantially impact clinical decision-making and patient outcomes in pediatric bacteremia.

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