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Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
Voice disorders in HIV-infected individuals: a preliminary study
1Department of Audiology and Speech Language Pathology, Kasturba Medical College, Manipal University, Mangalore, Karnataka 575001, India. milimm1@yahoo.co.in
International Journal of STD & AIDS
|November 17, 2007
Summary
This study found that Human Immunodeficiency Virus type 1 (HIV-1) infection impacts vocal parameters in individuals with HIV/AIDS. Voice analysis revealed widespread vocal impairments, even without direct vocal fold pathology.
Area of Science:
- Neurology
- Speech-Language Pathology
- Virology
Background:
- HIV-1 infection affects the central and peripheral nervous systems, leading to communication deficits.
- Progressive decline in speech, language, cognition, and swallowing is observed in early HIV infection stages.
Purpose of the Study:
- To profile vocal impairments in individuals with HIV/AIDS.
- To support evidence-based assessment and management practices for HIV-related communication issues.
Main Methods:
- Inclusion of eight participants diagnosed with HIV/AIDS.
- Subjective voice analysis by a speech pathologist.
- Objective acoustic analysis using Kay Elemetrics MDVP software.
Main Results:
- All participants exhibited affected voice parameters.
- Vocal parameter impairments ranged from one to all analyzed parameters across subjects.
- Voice production mechanisms were not always directly affected, yet vocal parameters were compromised.
Conclusions:
- Preliminary findings indicate widespread vocal parameter alterations in HIV-infected individuals.
- Further research is needed to establish a definitive correlation between vocal deviations and specific medical conditions in HIV/AIDS.
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