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Updated: Jul 10, 2026

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines
Published on: September 13, 2017
[Osteoporosis in cancer survivors]
José Manuel Olmos Martínez1, Jesús González Macías
1Departamento de Medicina Interna. Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander. Cantabria. España. miromj@humv.es
Abstract:
The detection of late sequelae in survivors of cancer has become increasingly important as developments in diagnostic and therapeutic methods have led to a more and long-term survival rates in tumoral patients. Osteoporosis is one of such problem that has been increasingly identified in patients with cancer. Significant bone loss and increased risk of fractures have been described in these patients. Medical problems associated with the malignancy or caused by the oncologic treatment are the main factors involved in bone loss. Therefore, patients at risk for bone loss should be undergo preventive or therapeutic interventions at an early enough stage to prevent fractures.
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