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Updated: Jul 10, 2026

Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights
Published on: October 13, 2023
Extra-skeletal Ewing's sarcoma of the submandibular gland
Hakan Agir1, Helen D Brasch, Swee T Tan
1Head and Neck and Skull Base Surgery/Oncology Programme, Wellington Regional Plastic, Maxillofacial and Burns Unit, Hutt Hospital, Private Bag 31907, High Street, Lower Hutt, New Zealand.
Abstract:
Extra-skeletal Ewing's sarcoma (EES) is an uncommon malignancy, especially in the head and neck region that may arise in various extra-osseous tissues. We report a 22-year-old male with an EES of the submandibular gland, which to the best of our knowledge, has not been described previously. The patient who underwent combined treatment with surgical resection and chemo-irradiation was disease free for 22 months but succumbed to multi-organ metastases 14 months later. This case highlights the combined diagnostic role of immunohistochemical, cytogenetic and radiological evaluation of EES. EES is an aggressive cancer that requires multidisciplinary management with wide surgical excision and adjunctive chemo-irradiation for the best outcome.

