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Cytochromes P450 and drug discovery

David C Lamb1, Michael R Waterman, Steven L Kelly

  • 1Institute of Life Science, Swansea Medical School, Grove Building, Swansea University, Swansea SA2 8PP, UK. d.c.lamb@swansea.ac.uk

Current Opinion in Biotechnology
|November 17, 2007
PubMed
Summary

Cytochromes P450 (CYP) are crucial proteins in drug metabolism and natural product biosynthesis. This review explores their roles as drug targets and in drug development through CYP engineering for medicinal and biotechnological applications.

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