Improving the conduct of epidemiologic studies: an introduction to quality principles

The process of conducting and ensuring the quality of epidemiologic studies has received little attention in the published literature. In concert with the variable nature of observational research, this has created a perceived need for guidelines relating to the conduct and reporting of epidemiologic studies. Amendments to two recent government regulations stipulate that epidemiologic studies should be carried out in accordance with as yet unspecified guidelines. Yet, guidelines alone will not improve the quality of epidemiologic studies. A more comprehensive approach is envisioned with reference to specific quality improvement principles used in industry.