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Published on: June 10, 2021
Synthesis and X-ray structure of a new pyrrolo[1,2-b]-pyridazine derivative
Mino R Caira1, Florea Dumitrascu, Constantin Draghici
1Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa. xraymino@science.uct.ac.za
Abstract:
The synthesis, characterization and X-ray crystal structure of 2-(4-chloro-phenyl)-7-methylpyrrolo[1,2-b]pyridazine are reported. The compound crystallizes in the space group P2(1)/c (No.14) with a =3.8568(1), b = 11.0690(3), c = 26.4243(7) A, beta =92.777(1) degrees and Z = 4. Accurate molecular parameters for the novel heterocyclic system were obtained from intensity data collected at 113K. The molecule assumes a planar conformation in the crystal and the packing is based on pi-pi stacking with interplanar spacing 3.400 å, typical of aromatic molecules with potential for displaying useful optical properties.
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