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Flavone glycosides from Calycotome villosa Subsp. Intermedia
Ali El Antri1, Ibtissam Messouri, Rachida Chendid Tlemçani
1Laboratoire d'Analyses, d'Essais et d'Environnement (L.A.E.E.), Département de Chimie, Faculté des Sciences Dhar Mehraz, Université Sidi Mohamed Ben Abdellah, 30000 Fès, Morocco.
Molecules (Basel, Switzerland)
|November 17, 2007
Summary
Two flavonoids, chrysin glucoside and a new acetylated derivative, were isolated from Calycotome Villosa Subsp. Intermedia. Their structures were confirmed using spectroscopic methods.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
Background:
- Flavonoids are a diverse group of plant secondary metabolites with various biological activities.
- Calycotome Villosa Subsp. Intermedia is a plant species that may contain novel bioactive compounds.
Purpose of the Study:
- To isolate and characterize flavonoid compounds from Calycotome Villosa Subsp. Intermedia.
- To identify a new glycoside flavone from this plant source.
Main Methods:
- Extraction of compounds from flowers and leaves of Calycotome Villosa Subsp. Intermedia.
- Isolation of major fractions and new compounds.
- Structure elucidation using UV-Vis, 1R, (1)H-, (13)C-NMR, and ESI-MS techniques.
Main Results:
- Isolation of the known flavonoid chrysin-7-O-(beta-D-glycopyranoside) (chrysin glucoside) as a major fraction.
- Identification of a new glycoside flavone, chrysin-7-O-beta-D-[(6"-acetyl)glycopyranoside].
- Confirmation of structures through comprehensive spectroscopic analysis.
Conclusions:
- The phytochemical investigation of Calycotome Villosa Subsp. Intermedia yielded two significant flavonoids.
- The discovery of a new acetylated flavonoid highlights the potential of this plant for novel compound discovery.
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