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Predicting antipsychotic use in children.

Ken Gersing¹, Bruce Burchett, John March

¹Department of Psychiatry, Duke University Medical Center, Durham, NC, USA. gersi@001@mc.duke.edu

Psychopharmacology Bulletin

|November 17, 2007

Summary

Boys and African American children are more likely to use atypical antipsychotics. Further research is needed to understand the reasons for this trend in psychotropic medication use.

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Area of Science:

Child and Adolescent Psychiatry
Psychopharmacology
Health Services Research

Background:

Psychotropic medication use in children and adolescents is increasing.
Previous reports indicated higher atypical antipsychotic use in boys compared to girls.
The reasons for gender disparities in prescription patterns were previously unclear.

Purpose of the Study:

To investigate the factors contributing to the use of atypical antipsychotics in pediatric patients.
To examine the roles of race, gender, age, and diagnosis in atypical antipsychotic prescription patterns.

Main Methods:

Analysis of an anonymous clinical mental health database from Duke University Medical Center (1999-2005).
Inclusion of 3,268 patients (under 18) with 7,701 visits.
Extraction of demographic data (age, gender, race) and diagnosis as predictors for atypical antipsychotic use.

Main Results:

Males and older children showed higher likelihood of atypical antipsychotic use.
African American children were slightly more likely to use atypical antipsychotics than white children.
Patients with psychotic or internalizing diagnoses were more prone to antipsychotic prescription.

Conclusions:

The study identified demographic and diagnostic factors associated with atypical antipsychotic use in youth.
Further investigation is warranted to understand the underlying reasons for higher use in boys and African American children.