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Updated: Jul 10, 2026

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
Published on: May 2, 2018
Predicting antibiotic resistance
José L Martínez1, Fernando Baquero, Dan I Andersson
1Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública and Unidad Asociada al CSIC Resistencia a los Antibióticos y Virulencia Bacteriana, Cantoblanco, 28049-Madrid, Spain. jlmtnez@cnb.uam.es
Abstract:
The treatment of bacterial infections is increasingly complicated because microorganisms can develop resistance to antimicrobial agents. This article discusses the information that is required to predict when antibiotic resistance is likely to emerge in a bacterial population. Indeed, the development of the conceptual and methodological tools required for this type of prediction represents an important goal for microbiological research. To this end, we propose the establishment of methodological guidelines that will allow researchers to predict the emergence of resistance to a new antibiotic before its clinical introduction.
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