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Crystallization and preliminary diffraction analysis of caudoxin and notexin; two monomeric phospholipase A2
D L Scott1, A Achari, P A Christensen
1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.
Abstract:
Two monomeric neurotoxic phospholipases A2 have been crystallized and their diffraction properties characterized. Crystals of caudoxin (from the venom of Bitis caudalis) and notexin (from the venom of Notechis scutatus scutatus) were grown at neutral pH, in the absence of calcium ion, and diffract to a resolution of 2.3 and 1.6 A, respectively.