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Updated: Jul 10, 2026
05:39
Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
[Malignant lymphoma of the thyroid]
Hidemi Ohye1, Shuji Fukata, Mitsuyoshi Hirokawa
1Department of Internal Medicine, Kuma Hospital.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|November 21, 2007
Summary
Primary thyroid lymphoma, often linked to Hashimoto's thyroiditis, typically affects women over 60. Early diagnosis and tailored treatments like chemotherapy or radiation improve outcomes for this non-Hodgkin lymphoma.
Area of Science:
- Oncology
- Endocrinology
- Pathology
Context:
- Primary thyroid lymphoma is a rare malignancy.
- Frequently associated with Hashimoto's thyroiditis.
- Predominantly affects postmenopausal women.
Purpose:
- To summarize the key aspects of primary thyroid lymphoma.
- To highlight diagnostic and treatment strategies.
- To emphasize the importance of early detection for prognosis.
Summary:
- Usually a non-Hodgkin type, common in women around 60.
- Characterized by a rapidly growing goiter.
- Histopathologic types include extranodal marginal zone B-cell lymphoma and diffuse large B-cell lymphoma.
- Diagnosis requires histopathological confirmation via open biopsy if ultrasonography and fine needle aspiration cytology are suspicious.
- Treatment involves chemotherapy (CHOP), rituximab with CHOP, or radiation therapy, chosen based on type and stage.
- Prognosis is dependent on histopathologic type and disease staging.
Impact:
- Underscores the need for prompt diagnosis and appropriate treatment.
- Recognizes that early intervention significantly improves patient outcomes.
- Contributes to better understanding and management of thyroid lymphomas.
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