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Case of biliary lithiasis in an infant
1Institute of Pathology and Immunopathology, Tg. Mureş, Romania.
Summary
A premature infant experienced fatal hemorrhage from a giant hemangioma. The infant also had gallstones, likely due to hemolytic episodes in an immunodeficient state.
Area of Science:
- Pediatric Pathology
- Neonatal Medicine
- Vascular Malformations
Background:
- Premature infants are susceptible to various complications.
- Giant hemangiomas can lead to significant morbidity and mortality.
- Biliary lithiasis in infants is uncommon and warrants investigation.
Observation:
- A 3-month-old premature infant presented with massive hemorrhage.
- The hemorrhage originated from a giant hemangioma in the right thigh.
- The infant also had six dark-green-blackish faceted gallstones.
Findings:
- The gallstones were composed of biliary pigment.
- These calculi are likely a consequence of repeated inflammatory hemolytic episodes.
- The infant had an underlying immunodeficient condition.
Implications:
- This case highlights the potential for severe complications in premature infants with giant hemangiomas.
- It underscores the association between hemolytic episodes, immunodeficiency, and biliary pigment calculus formation.
- Further research into the pathogenesis of biliary lithiasis in immunocompromised infants is warranted.