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[Endoscopic and conservative treatment of vesicoureteric reflux]

Z Dítĕ1, R Kocvara, J Dvorácek

  • 1Urologická klinika 1. LF UK a VFN, Praha. zdenekdite@seznam.cz

Casopis Lekaru Ceskych
|November 21, 2007
PubMed

Insights

Endoscopic treatment for vesicoureteric reflux (VUR) using dextranomer instillation is a safe and effective option for children, offering better outcomes than conservative management. This minimally invasive approach shows a high success rate with few complications.

Area of Science:

  • Urology
  • Pediatric Surgery
  • Minimally Invasive Procedures

Context:

  • Vesicoureteric reflux (VUR) affects children, potentially leading to kidney infections and damage.
  • Conservative management has limited success rates for moderate to severe VUR.
  • Endoscopic treatment offers a less invasive alternative to open surgery.

Purpose:

  • To compare the efficacy of endoscopic dextranomer (Dx/Ha) instillation versus conservative treatment for VUR in children.
  • To evaluate the success rates and complication profiles of both treatment modalities.
  • To assess long-term outcomes of VUR treatment in pediatric patients.

Summary:

  • A prospective randomized study compared endoscopic Dx/Ha instillation (22 children) with conservative management (22 children) for VUR grades 3-5.
  • The endoscopic group achieved a cure rate of 54.5% and improvement in 66.7% of cases.
  • The conservative group showed a cure rate of 22.7% and improvement in 18.2% of cases, with significantly lower success rates.

Impact:

  • Endoscopic dextranomer instillation is a safe and effective treatment for pediatric VUR across all age groups.
  • This minimally invasive procedure yields good therapeutic outcomes with minimal adverse effects.
  • The findings support endoscopic treatment as a preferred option for VUR, potentially reducing long-term renal complications.
Abstract

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