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Related Concept Videos

Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Microvilli00:55

Microvilli

Microvilli are tiny finger-like projections found on the surface of certain cells. Their purpose is to increase the surface area of the cell's apical surface, resulting in more effective absorption or secretion of substances.
These microvilli are predominantly present in cells lining the small intestine, kidney tubules, and certain cells in the respiratory and reproductive systems. By significantly expanding the surface area of the cell membrane, microvilli enhance the cell's capacity to...
Mucosal Barrier of the Stomach01:25

Mucosal Barrier of the Stomach

The gastric glands contain parietal cells that secrete hydrochloric acid (HCl) for digestion. The cells secrete HCl because it is highly corrosive and essential for breaking down food. To achieve this, they secrete hydrogen and chloride ions into the lumen of the gastric glands, which combine to form HCl.
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...

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Related Experiment Video

Updated: Jul 10, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

[Mucocele of the appendix].

Miguel Echenique-Elizondo1, Carlos Liron de Robles, José Antonio Amondarain Arratíbel

  • 1Universidad del País Vasco, Departamento de Cirugía, Hospital Donostia, San Sebastián, Guipúzcoa, España. gepecelm@sc.ehu.es

Cirugia Espanola
|November 21, 2007
PubMed
Summary

Appendiceal mucoceles are rare, with over 40% of cases associated with other neoplasms. Long-term monitoring is recommended due to the risk of pseudomyxoma peritonei.

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Three-dimensional Quantification of Intestinal Mucus Using Whole-mount Tissue Imaging
05:10

Three-dimensional Quantification of Intestinal Mucus Using Whole-mount Tissue Imaging

Published on: September 12, 2025

Related Experiment Videos

Last Updated: Jul 10, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Three-dimensional Quantification of Intestinal Mucus Using Whole-mount Tissue Imaging
05:10

Three-dimensional Quantification of Intestinal Mucus Using Whole-mount Tissue Imaging

Published on: September 12, 2025

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Appendiceal mucoceles are uncommon, representing 0.25% of appendectomies and 8% of appendiceal tumors.
  • This study reviews 27 cases of appendiceal mucocele treated over a 28-year period.

Purpose of the Study:

  • To analyze the clinical presentation, management, and outcomes of appendiceal mucocele.
  • To investigate the association of appendiceal mucoceles with other neoplasms and pseudomyxoma peritonei.

Main Methods:

  • Retrospective review of 27 appendiceal mucocele cases treated at Donostia Hospital (1978-2006).
  • Analysis of patient demographics, surgical indications, operative findings, and follow-up data.

Main Results:

  • The average patient age was 54.4 years, with a slight male predominance (55.5%).
  • Emergency surgery was performed in 62.9% of cases, often for lower right abdominal pain.
  • A significant finding was the 40.7% incidence of synchronous or metachronous neoplasms in other locations; three patients developed pseudomyxoma peritonei.

Conclusions:

  • Appendiceal mucoceles require vigilant long-term monitoring.
  • The potential association with other neoplasms and the risk of pseudomyxoma peritonei necessitate ongoing surveillance.