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Related Experiment Video

Updated: Jul 10, 2026

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft

Published on: February 14, 2022

Current trends in cardiac transplantation.

Deborah G Klein¹

¹Cardiac Intensive Care Unit and Heart Failure Special Care Unit, Cleveland Clinic, Cleveland, OH, USA. kleind@ccf.org

Critical Care Nursing Clinics of North America

|November 21, 2007

Summary

Cardiac transplantation is a leading treatment for advanced heart failure in patients under 65. Success is due to liberal selection, effective immunosuppression, and rejection management.

Area of Science:

Cardiology
Transplantation Medicine

Background:

Cardiac transplantation is the primary therapy for advanced heart failure in patients under 65.
It is indicated for symptomatic patients despite maximal medical therapy.

Purpose of the Study:

To present the current status of cardiac transplantation.
To review recipient and donor selection, surgical techniques, postoperative care, immunosuppression, and rejection management.

Main Methods:

Review of current practices in cardiac transplantation.
Analysis of recipient and donor selection criteria.
Evaluation of immunosuppression and rejection management strategies.

Main Results:

Cardiac transplantation success is attributed to liberal selection criteria, effective immunosuppression, and rejection management.

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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

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Last Updated: Jul 10, 2026

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft

A Porcine Heterotopic Heart Transplantation Protocol for Delivery of Therapeutics to a Cardiac Allograft

Published on: February 14, 2022

Cardiac Loading using Passive Left Atrial Pressurization and Passive Afterload for Graft Assessment

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Published on: August 2, 2024

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

Current protocols cover selection, surgery, postoperative care, and immunosuppression.

Conclusions:

Cardiac transplantation is a well-established treatment for advanced heart failure.
Ongoing challenges include organ allocation, but management strategies ensure success.